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Researchers at the Joslin Diabetes Center have been researching ways to generate fat loss by stimulating brown fat production.

In a recent study (published in Nature), they have shown that a protein called BMP-7 can promote the development of brown fat.

This is good news.

While the white fat cells that cover our doughy North American bodies are seen as the bane of our collective overweight existence, their brown fat cousins are superstars at burning calories.

What?

Yep. You read that right. Fat that burns calories.

The primary function of brown fat is to generate body heat.

In contrast to white fat cells, which contain a single lipid (fat) droplet, brown adipocytes contain numerous smaller droplets and a much higher number of mitochondria.

But more importantly, the main role of brown fat is to burn calories by generating heat.

Sadly, brown fat cells largely disappear by adulthood in humans, but their precursors still remain in the body.

It is these brown fat precursors that the researchers were targeting.

The Science

A 2005 Joslin study discovered genes that control the creation of the precursor cells of brown fat.

A 2007 Joslin study found clusters of brown fat cells dispersed between bundles of muscle fibers in an obesity-resistant strain of mice.

This latest study identified BMP-7 as the protein capable of causing the formation and activation of brown fat cells.

Knowing this, the researchers injected the mice with BMP-7.

Success!

According to the researchers, delivery of BMP-7 into mice using adenovirus as a vector resulted in an increase in the growth of brown fat.

In one of the experiments, the mice that developed brown fat tissue gained less weight than those that did not.

In another experiment, mice that received injections of progenitor cells, (similar to stem cells) that had been pre-treated with BMP-7 also developed additional brown fat tissue.

[caption id="attachment_792" align="alignnone" width="241" caption="The difference between Stem cells and Progenitor cells"][/caption]

So what does this all mean?

• The researchers were trying to discover what controls the development of brown fat cells.

• They already knew that BMPs are a group of proteins known to regulate the formation of a baby's organs during their embryonic development.

• Their current research indicates that BMP-7 (and perhaps other BMPs) can control the fate of brown and white cells.

Brown and white fat cells.

Turn one on and the other off.

Turn on 'calorie burning' fat and turn off 'calorie storing' fat.

Now that is exciting.

More info on scientific research into obesity - here.
More info into dietary intervention of obesity - here.
More info on exercise intervention of obesity - here.

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Nasi Lemak which was similar to the one at Sea Park. Sea Park's one is still much better!

Traded my Neon Colored Dunkesto to eman for Air Jordan 1 BMP (Old Love).. Weeeheee! Superr random..

Air Jordan 1 Beginning Moments Pack (Old Love)..

And I wore them to college on Saturday, and then to Starbucks and witnessed a fight between to grown up men about toilet... Hmmm...

Broke into these on Saturday... I guess I still need to get the angle right to snap pictures of "What you rocking today" with a 50mm lens.. I can do it with a wide and its boring.. Hahaha..

Headed to Digital Mall and spend a bit (refused to join the craze at PC fair).. Headed to Shah Alam and then to Subang for dinner.. And played Rayman Raving Rabbits on Wii for the whole night.. Hammering rabbit was fun! Hahahhaah...

That's all for now and I am trying hard not to let this place die...

WMV (Windows Media Video) is a name for the set of video codec technologies developed by Microsoft.
WMV files use ASF container format. These files can be played by MPlayer or Windows Media Player.

The .wmv file extension usually describes ASF files using Windows Media Video codecs. The audio codec used with WMV is normally a version of WMA.

Besides ASF, WMV can be put into the AVI or MKV container formats as well.

Originally the WMV codec was designed for Internet streaming applications. Two other codecs - WMV Screen and WMV Image - are a screencast codec and a video slideshow codec respectively.

BMP (or DIB) is a
bitmapped graphics format used commonly as a simple graphics file format on the Microsoft Windows and OS/2 platforms.
In BMP files images are generally stored with a color depth from 2 (1-bit) to 16.7 million (24-bit) colors. 8-bit images instead of indexed color can be greyscale. Alpha channels may be stored in a separate files, similar to a greyscale image.

As BMP files are usually not compressed they are much larger than compressed image file formats for the same image.
Most BMP files compress very well with lossless data compression algorithms such as ZIP because they contain redundant data.

In the tables that follow, we'll assume all offsets start at zero, all field sizes are in bytes, and all numeric values are stored with the least significant byte first.

Bitmap (BMP)

The first two bytes of the Bitmap file and header will identify its image format.

Windows BMP files begin with a 54-byte header:

OS/2 BMP files begin with a 26-byte header:

PCX files begin with a 128-byte header:

JPEG Header Format:

Strictly speaking, JPEG files do not have formal headers, but fg_jpeghead() and fgi_jpeghead() return relevant information from the file's start of frame segment. We call it a header for consistency with other image file formats. The first part to look at is the first two bytes of the file. The hex values FF D8 will identify the start of the image file. This is often enough to know that you have an actual JPEG file. The next two bytes are the Application marker typically FF E0. This marker can change depending on the application used to modify or save the image. I have seen this marker as FF E1 when pictures were created by Canon digital cameras. The next two bytes are skipped. Read the next five bytes to identify specifically the application marker. This would typically be 4A 46 49 46 (JFIF) and 00 to terminate the string. So, it is FF D8 FF E0 <skip two bytes> 4A 46 49 46 00

TIFF (Tag Image File Format):

The image header for a TIFF image is a fixed 8 byte segment always occurring at the beginning of the file. To ensure TIFF images can be read properly by PC's (Intel processors) and Macintosh computers the header must indicate a byte order which in this case is the first two bytes of the file. The first two bytes will either be hex 49 49 (II) for Intel format or 4D 4D (MM) for the Macintosh integer format which was based on Motorola processors. The next byte is 2A (decimal 42). This number should never change. The number 42 was used because of it's significant meaning in mathematics, religion, science, and other fields. Ignore the rest of the header. For our purpose of identifying the image format these bytes are all that we need to look at.

GIF (Graphics Interchange Format)
A GIF file is a compressed image format. It uses lossless data compression which is also used in zip and gzip functions. Lossless data compression ensures that there is no data loss or image degradation. GIF files are largely used for animated images and in the early years of the internet you would be hard pressed to find a website not using some form of animated GIF file.

To identify the GIF file read the first three bytes of the file.

AVI Header Format:

AVI files contain a 56-byte header, starting at offset 32 within the file.

Examples

This is a basic example for checking the header file for the above mentioned file formats. This code will not compile on its own.


VerifyImageType PROCEDURE (STRING fileNameAndPath, *STRING myErrorDescription)

imageFileExt STRING(4), AUTO

imageFileName STRING(MAX_PATH_AND_FILENAME_LENGTH), AUTO
IMAGE_FILE FILE, DRIVER('DOS'),Name(imageFileName),PRE(IMFIL)
Record RECORD
fileBuffer STRING(10)
END
END
CODE

imageFileName = fileNameAndPath
myErrorDescription = ''

!Extract the file extension - not a built in function
IF ~GetfileExtension(imageFileName, imageFileExt)
!Report Error
myErrorDescription = 'Error getting file extension'
Return(FALSE)
END

Open(IMAGE_FILE, ReadOnly)
IF ErrorCode()
!Report Error
myErrorDescription = 'Error opening ' & Clip(imageFileName)
Return(FALSE)
END

Set(IMAGE_FILE)
Next(IMAGE_FILE)
IF ErrorCode()
myErrorDescription = 'No data found in image file'
Return(FALSE)
END

CASE Upper(Clip(imageFileExt))
OF 'JPG'
OROF 'JPEG'

IF IMFIL:fileBuffer[1:2] = '<0FFh,0D8h>'
!Success, File was recognized, Perform some task.
Return(TRUE)
ELSE
!Report error and Perform some task
myErrorDescription = 'Image header does not match the file extension'
Return(FALSE)
END

OF 'BMP'

IF IMFIL:fileBuffer[1:2] = '<042h,04Dh>'
!Success, File was recognized, Perform some task.
Return(TRUE)
ELSE
!Report error and Perform some task
myErrorDescription = 'Image header does not match the file extension'
Return(FALSE)
END

OF 'TIFF'
OROF 'TIF'

IF IMFIL:fileBuffer[1:3] = '<049h,049h,02Ah>'
!Success, File was recognized, Perform some task.
Return(TRUE)
ELSE
!Report error and Perform some task
myErrorDescription = 'Image header does not match the file extension'
Return(FALSE)
END

OF 'GIF'

IF IMFIL:fileBuffer[1:3] = '<047h,049h,046h>'
!Success, File was recognized, Perform some task.
Return(TRUE)
ELSE
!Report error and Perform some task
myErrorDescription = 'Image header does not match the file extension'
Return(FALSE)
END

ELSE
!Handle unsupported images if needed.
myErrorDescription = 'Error, non supported image extension encountered'
Return(FALSE)
END

The downside for typical users though, (other than its price – which is formidable), is it's huge size on disk, it’s very challenging platform requirements, and an extreme learning curve which demands time and training.

Most of us don’t need the flexibility, or the power of a high end (read expensive), photo editor. Instead, we’re looking for an application that’s small, fast, and free with an intuitive interface that’s very easy to use; especially for those with only modest previous experience.

IrfanView which is one of my favorite photo applications (not just mine; there have been over 34 Million downloads), is not just an image viewer, but an image browser, converter, and an editor as well. Best of all, you’ll find the interface intuitive and very easy to use. If you’re curious, this application is named after its developer Irfan Skiljan.

With IrfanView you can fix and enhance digital photos including resizing, cropping, correcting red eye, flipping, and rotating. As well, you can perform a wide variety of image adjustments, including brightness, contrast, and applying special effects such as sharpen and blur.

I have been using this neat little program for years and with every new release it just keeps getting better. The latest version - version 4.20, released July 16, 2008, includes plug-in support for most image, video, and sound formats, including MP3, AVI, audio CD, and WMA. An added bonus in the latest version is you now have the ability to Draw, Erase, Fill, Rotate, and Draw an Arrow.

Fast Facts:

Free

Small – only 1.2 MB

Many supported file formats

Multi language support

Thumbnail/preview option

Slideshow (save slideshow as EXE/SCR or burn it to CD)

Show EXIF/IPTC/Comment text in Slideshow/Full screen etc.

Support for Adobe Photoshop Filters

Drag & drop support

Fast directory view (moving through directory)

Batch conversion (with image processing)

Multipage TIF editing

Multimedia player

Print option

Change color depth

And much more

Unless you have unusual image editing requirements, IrfanView should more than meet your needs.

System Requirements: Windows Vista, Windows XP

Download at: Download.com

Isso mesmo que vocês veem na imagem, o cara vaiatés 320 bpm. ._.

Esse camarada tá no guiness. ê_e

Agora simplesmente vejam o vídeo. .-.

General Overview:
Project Dogwaffle is another fun replacement for paint. The version 1.2 is a freeware version of the original series. The paint-based program is impressive with its tools and functions. However, the turn off - native format. Hence, using this software to edit your favourite pictures becomes a chore. You will have to convert it using other programs like Irfanview. After all said, if you really want something that loads fast and provides paint functions that is somewhat like a Adobe Photoshop, this is still the software for you. It still has .bmp format to keep you happy.

FreewareAddict Rating: 7/10
It just lacks something.

Features:

Impressive drawing inventory

Tools like pastel, pencils, charcoal etc, very accessible!

Animation Functions

Some print screens of the animation making process.

Could not convert into a format to show everyone out here my masterpiece. XD
It is in .dwa, a troublesome format.

The bad point

The sad thing is that, you can only open bmp files.
Converting has to be done.

Closing comments:
Perhaps, they chose .bmp and created their own native format for some reasons. We are not sure, and maybe you can help us find out. Maybe, they did this to achieve faster systems. Other than that, a simple and worthy program to try out. If you are new to Adobe or other software, this program may be more simpler for you. If you want performance, why not try out the other programs feature here?

Supports : Windows XP, Windows Vista (Some bugs encountered on Vista)

The version we’ve tested is v1.2.
Official Website: http://www.thebest3d.com/dogwaffle/free/index.html (4.3Mb)

Bob after his makeover. No more blurred vision. Cool Glasses!

A:
Das ist korrekt. Nachdem die Faxe immer als Grafik vorliegen, werden die PDF Dateien die vom Fax Server erstellt werden - unabhängig vom Format des Originaldokuments - immer als Grafik (konkret als Tiff Grafik) erstellt.

--
Cornelia Wegmueller, Customer & Partner Support
ActiveFax Communication Group
a division of
INTERTRADE ENTERPRISES LTD :: Blegistr.25 :: CH-6340 Baar/Switzerland
Phone: +41 44 5866974  ::  Fax: +41 44 2742350
mailto:support@activefax-distribution.com

Corporate WebSites:
http://www.activefax-distribution.com
http://www.creacity-group.com
http://www.intertrade.cc

Now the development of the main executable and the design part of project Ninja will begin. Tomorrow we are going to adjust the old batcher and add them to the main executable and starting Wednesday we are going to start designing the full interface later to also add it to the main executable.  This will probably be our biggest obstacle as the interface will be a huge change and will make most of the weight of 36-image converter executable.

The new core will be based on the old one (CN:Lapiz) but will be new in some aspects so the new core is codenamed : "Azul". Azul will be more reliable and will have better support for big images.

We have also made a few icons, we only have to choose the best one. We aren't going to put a real date on the release but you might expect 36-image converter 4.4 still this month.